Treatment Strategy

Before treating erectile dysfunction (ED), it is important to consider the health status of the patient, the expectations he and his partner may have for treatment, and the impact of resuming sexual activity. The first line of therapy for ED is use of oral medications (phosphodiesterase-5 inhibitors such as CIALIS that work by increasing blood flow in the penis, allowing the development of an erection with sexual stimulation.1

Second-line therapy involves the use of intracavernosal injection therapy, vacuum device therapy, and transurethral agents.1 Third-line therapy is confined to penile implant surgery and vascular surgery.2

Identifying a patient’s individual needs

When determining whether CIALIS may be an appropriate treatment option, consider the patient's clinical profile, including but not limited to:

Nitrate use- CIALIS is contraindicated in men who are taking any form of organic nitrate, as the combination can cause an unsafe drop in blood pressure.1,3

Cardiovascular status- CIALIS should not be used in men for whom sexual activity is inadvisable as a result of their underlying cardiovascular status.1,3 Advise patients to seek immediate medical attention if they experience symptoms such as chest pain, dizziness, or nausea during sex. CIALIS was not studied in and is not recommended for the following groups of patients: those with MI within the last 90 days; unstable angina or angina during sexual intercourse; stroke or heart failure within the last 6 months; uncontrolled arrhythmia; hypotension; and uncontrolled hypertension.3

Other comorbid conditions- CIALIS is not recommended for patients with certain conditions, including degenerative retinal disorders or severe hepatic impairment.3Dosing adjustments for patients with mild or moderate hepatic or moderate renal impairment may be required. CIALIS should be used with caution in patients who have conditions that may predispose them to priapism or in patients that have an anatomical deformation of the penis.

Potential drug interactions- Use of CIALIS with alpha-blockers, antihypertensives, or substantial amounts of alcohol (>=5 units) may lead to hypotension. CIALIS for once daily use provides continuous plasma levels, which should be considered when evaluating the potential for interactions.

See full Prescribing Information for additional Important Safety Information.


HKGCIA2015-09-29T13_29_38


1Lue TF. Drug therapy: erectile dysfunction. N Engl J Med. 2000;342:1802-1813.
2NIH Consensus Conference. Impotence. NIH Consensus Development Panel on Impotence. JAMA. 1993;270:83-90.
3Hong Kong Cialis Product insert, version PA007SPHK01


Last Update: 6 Oct 2015

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